Dr. Bachmann is advancing Pancreatic islet transplantation approaches for the treatment of diabetes using imaging, he is also developing the tools for in vivo genomic strategies for the study of immune cell migration patterns and immune surveillance of cancer.

Dr. Cao has described the early events in hematopoiesis by imaging the engraftment and proliferation of small numbers of hematopeitic stem cells. The imaging strategies that he has developed are now being applied to the study of factors that control engraftment and direct stem cell homing.

Dr. Hardy studies the mechanisms of pathogenesis and immune control of infection in several models and has applied imaging strategies to reveal novel sites of infection and unique replication patterns of Listeria monocytogenes in vivo.

Dr. Wang has advanced the field of in vivo confocal microscopy using a dual axes architecture of confocal and is miniaturizing this design using MEMS technologies. Dr. Wang is a gastroenterologist and is moving these technologies to the study of GI diseases.

Dr. Doyle is developing reporter gene strategies that will advance in vivo discovery approaches and is using these tools for the development of in vivo genomic strategies for the study of the regulatory networks that control metastatic disease in breast and prostate cancer.

Dr. O'Connell-Rodwell has used imaging strategies to dissect the molecular physiology of thermal stress as a step toward the improvement of microsurgical approaches using lasers. Dr. O'Connell-Rodwell is also using molecular imaging approaches to advance our understanding of hearing loss with the hope of improving therapies for the deaf.

Dr. Zhao is developing dual function reporter genes and using these to reveal the regulatory pathways of cellular response to hypoxia in glioma models. She is also studying the role of DNA methylation in the regulation of heme oxygenase I expression.

Dr. Mandl used multimodality imaging approaches to dissect the molecular basis of cell death as tumors respond to chemotherapeutic agents. She also advanced immune cell therapies for cancer. She is now working at Exelixis, Inc.

Dr. Burns is a microbiologist interested in studying the host response to infection and the differences in innate immunity in young and old animals relative to GI infections.

Dr. Duda is investigating the determinants of stem cell engraftment and proliferation in hematopoeisis.

Dr. Wang is investigating the duration of the effects of siRNA on inducible gene expression.

Dr. Shinde is a chemical engineer who is developing new chemistries for in vivo sensing.

Dr. Thorne is advancing oncolytic viral therapies for cancer and the tools that would enhance systemic delivery.

Dr. Morioka is studying ischemia and gene expression in stroke models.

Ms Lee is studying mother to infant transmission of HIV in a cohort from Zimbabwe in a collaboration with Dr. David Katzenstein.

Mr. Eimerman is a graduate student in Microbiology and Immunology and has been evaluating pathogenesis determinants in pseudomonas infections.

Ms. Kemper leads the efforts in transgenic mouse production and breeding.

Mr. Reeves has been studying the determinants of stem cell engraftment in hematopoeisis.

Ms. Kalish is studying host response to infection using transgenic reporter animals.

Ms. Ravindran is an undergraduate in biology and is evaluating the regulatory pathways that control BMP4 expression during development.

Jonathan is a graduate student at Stanford who is developing computational tools for data management in imaging.

Ms. Glennon is the administrative assistant for the laboratory.